Biotech Training And Research Centre In Lucknow | Experiome

The area of molecular docking has grown in popularity over the last three decades as structural molecular biology and structure-based drug discovery have become pivotal with time. The tremendous increase in the availability and power of computers, as well as the increased ease of access to small chemical and protein databases, have considerably aided it. The purpose of automated molecular docking software is to comprehend and predict molecular recognition on both a structural and energetic level, predicting binding affinity. Molecular docking is most commonly done between a small molecule and a macromolecule target. Although ligand–protein docking is commonly used, protein–protein docking is gaining popularity. Biotech Course Structure–activity studies, lead optimization, virtual screening for potential leads, providing binding hypotheses to aid predictions for mutagenesis studies, assisting x-ray crystallography in the fitting of substrates and inhibitors to electron density, chemical...

 Cloning and Recombinant DNA technology are same: Dilemma to be resolved A clone is a group of unique cells or organisms that derive from a single progenitor in biology. Because cell replication creates identical daughter cells every time, the individuals of a clone are genetically identical. The term "clone" has been extended to recombinant DNA technology (RDT), which allows scientists to make multiple copies of a single segment of DNA, such as a gene, resulting in identical duplicates that make up a DNA clone. In practice, a DNA fragment is inserted into a small DNA molecule, which is then allowed to proliferate inside a primitive live cell such as a bacterium. A DNA vector is a tiny self-replicating molecule (carrier). Plasmids (circular DNA molecules derived from bacteria), viruses, and yeast cells are the most commonly used vectors. Plasmids are not part of the main cellular genome, but they can include genes that provide the host cell valuable characteristic...

What is Genome Annotation? The process of identifying the locations of genes and all of the coding sections in a genome, as well as establishing what those genes perform, is known as genome annotation. It's required because DNA sequencing generates sequences with uncertain functions. Genome annotation has progressed over the last three decades from computational annotation of long protein-coding genes on single genomes and experimental annotation of short regulatory elements on a small number of them to population annotation of single nucleotides on thousands of individual genomes. Biotech Course This improved precision and inclusivity of genome annotations (from genotypes to phenotypes) is resulting in more precise insights into the biology of species, communities, and people. Genome annotation includes three major steps: 1. Identifying regions of the genome that do not encode proteins; 2. Identifying genome fundamentals, a process known as gene prediction; and 3. ...

  Experiome Inc organised a 2-day workshop on "Hands-on Practical Experience in Molecular Biology Techniques" under the aegis of RR Institute of Modern Technology, Lucknow on June 7-8, 2002. The students performed plasmid isolation, RNA isolation and agarose gel electrophoresis. Dr (Major) Neerja Masih delivered the Guest Lecture. The students were awarded certificates after the successful completion of the workshop. Team Experiome would like to thank Dr Dheerendra Kumar, HoD Biotechnology, RRGI. Team Experiome is highly grateful to the management of RRGI for providing this opportunity. Connect with us.. Life Science Training Centre in Lucknow | Biotech Research Centre in Lucknow | Biotech Course | Postgraduate Courses in Biotechnology

  Human genome Project Renato Dulbecco was the first to propose sequencing the human genome in 1984 to understand about cancer. The National Academy of Sciences in the United States first proposed HGP in 1988, followed by the National Institutes of Health and the Department of Energy. In 2003, the project was publicly established and declared. This project is still the largest collaborative biological effort in the world. Australia, Brazil, Canada, France, Germany, Japan, and the United Kingdom are among the countries participating in the initiative. It was a big problem to map out genes despite spending a large sum of money on it, starting at around $3 billion. In addition, the project experts revealed that roughly 1.5 percent of DNA leads to the synthesis of proteins. This raises the question of what the other 98.5 percent of DNA, known as non-coding DNA, performs. Summer Internship for Biotechnology Students in Lucknow . Over the last 20 years, scientists have had unpreceden...

  CRISPR-Cas use to meet the need of Vitamin A Nutrition is essential for healthy growth and development. Macronutrients or micronutrients are the two types of nutrients.   Macronutrients include fats, protein, carbohydrates and other nutrients. However, micronutrients that include vitamins and minerals are more important.   The amount of micronutrients in a child's diet can have an effect on their mental and physical development. Training Programs in Bioinformatics in Lucknow Vitamin A is a lipid soluble vitamin. It is necessary for cell growth and metabolism.   Vitamin A can naturally be found in dark leafy greens and orange-colored vegetables as well as milk products, liver and fish. Vitamin A deficiency can be a concern for children living in poverty.   UNICEF states that one-third of children don’t get vitamin A supplements, while WHO estimates that 190million pre-school children worldwide are vitamin A deficient. According to a National Nutrition Monitorin...